Edema disease is a complex and frequent gastrointestinal disorder that affects many weaned piglets every year. The main symptoms are mental disorders, edema of the eyelids, sometimes diarrhea, ankles, and finally loss of appetite, decreased growth performance, and increased mortality. The best way to prevent this disease during weaning pigs is to have veterinary treatment in a timely manner and maintain a good level of health (even if you do both, you may still have edema). In so many measures, although the nutritional strategy can not be completely prevented or cured, it can at least effectively alleviate the symptoms of edema. It should be emphasized that not every farm pays attention to nutrition strategies, and it is recommended that managers should use it as one of the effective methods to deal with edema disease. Because the nutritional strategy reduces diarrhea (caused by common E. coli), it also changes the composition of the specific serotype E. coli, effectively reducing the occurrence of edema (the edema disease is generally infected by Escherichia coli of a specific serotype). 1 zinc oxide Edema disease is more prevalent in areas where antibiotics and antibiotics are restricted. For example, in northern Germany, weaned piglets in southern Denmark are strictly introduced. There is basically no discomfort in the initial stage, but the edema disease is rapidly outbreak during the breeding process in Denmark. Never happened. Relevant experts attributed the lack of zinc oxide in German weaned pig feed (German banned), and zinc oxide as an additive is very resistant to edema disease. The zinc content in the feed is generally 3000 mg/kg, which is sufficient to treat E. coli infection. 2 antibiotics A recent study in Denmark showed that 27 strains of O139 Escherichia coli that caused edema were resistant to broad-spectrum antibiotics, 80% showed resistance to sulfonamides, but to colistin, gentamicin. , apramycin and amoxicillin / clavulanic acid sensitive. Antibiotics are also allowed in many parts of the world, which can prevent the sudden onset of edema. Therefore, careful and appropriate use of antibiotics in veterinary treatment should be recognized. 3 diet protein Many pathogens, including E. coli, use the crude protein in the substrate as a nitrogen source for proliferation. Therefore, the crude protein level of the weaned piglets with edema disease needs to be lowered by 2-4 percentage points, but the amino acid balance should be maintained. Similarly, the use of crystalline amino acids and protein materials with high digestibility can increase the crude protein digestibility of weaned piglets, which is beneficial to reduce the amount of undigested crude protein in the intestine. In fact, low nutrient density diets can also be used, but may result in insufficient nutrients for growth and development of weaned piglets and reduce growth performance. Thus, the bottom line for this approach is to strike a balance between loss of growth performance and cost savings. 4 other mineral elements In addition to zinc oxide, the addition of 250 mg/kg copper (copper sulfate form) to the full-price diet, if allowed, is also effective against bacterial infections, especially in the later stages of weaning piglets. Studies have shown that reducing the calcium content in the diet of weaned piglets (such as the maximum recommended amount of calcium in the first week of weaning in weaned pigs is 0.8%) can reduce the intestinal pH of weaned piglets and provide a good growth environment for beneficial bacteria. Finally, it must be remembered that E. coli breeds vigorously in iron-rich substrates, so try to keep the minimum iron requirement for weaned piglets in the diet. 5 nutrients It is generally believed that reducing or even not using soybean meal can greatly reduce the incidence of gastrointestinal diseases in weaned piglets, including edema disease. Although the cost of feed is greatly increased by using other protein materials instead of soybean meal, other protein materials are strongly recommended for weaned pigs with edema disease. Organic acids and some plant extracts can improve the intestinal environment and reduce the growth of harmful bacteria in the gastrointestinal tract. Composite organic or organic acids are generally more effective than inorganic acids in combination with plant extracts. 6-day ion balance Dutch scholars recently found that the same group of infected pigs and healthy pigs found that edema disease is not only related to intestinal E. coli infection, but also dietary factors can cause and aggravate edema disease. Infected pigs exhibit metabolic acidosis symptoms and a significant increase in blood and intestinal acidity. It is estimated that porcine metabolic acidosis, intestinal permeability will also increase, the toxin produced by E. coli through the intestinal barrier is greatly increased. Therefore, nutritional strategies may be beneficial in preventing edema disease, such as high levels of ion balance in the diet ((Na+K-Cl)) to prevent metabolic acidosis (different levels of ion balance in infected and healthy pig diets). 7 feeding management People pay too much attention to biosafety, health and general management conditions, and there are relatively few measures to prevent edema. First, limiting feeding for 4-5 days after weaning can reduce undigested feed into the intestines and avoid infection stress. When weaned pigs are seriously infected by bacteria, coarse particles instead of crushed particles can improve the overall health of the intestines; and when weaned pigs suffer from intestinal diseases, crushed particles are more likely to infarct in the intestines. Although these measures are beneficial for controlling intestinal diseases, the potential cost limits the growth performance of animals and should be carefully considered. Practical experience has shown that a 2-3 percentage point increase in crude fiber content can help weaned piglets resist various bacterial infections. Wheat and oat granules have better disease resistance and higher nutritional value than other crude fiber materials. Similarly, beet pulp sometimes works (unsure), and other pure crude fiber materials have different effects. The specific reasons need further study. 8 immunoglobulin The last mentioned edema disease solution is actually the most direct. The hen is inoculated with weaned piglet edema disease specific E. coli strain for multiple immunization, the eggs produced are rich in immunoglobulin, and the purified immunoglobulin is directly added to the feed. Once in the gastrointestinal tract, it binds to a specific E. coli strain, causing the pathogen to be inactivated. Recent studies have shown that after 68 days of weaning in the egg white immunoglobulin group, the weight of weaned piglets is 2.5 kg/head higher than that of the control group (edema disease, no added immunoglobulin), the mortality rate is reduced from 10% to 5%, and medical treatment The cost is also significantly reduced. Probe Digital Thermometer,Probe Digital Kitchen Meat Thermometer,Digital Thermometer Probe,Digital Bbq Thermometer Chengdu Augus Science Technology Co., Ltd. , https://www.vluckyaugus.com